Types of Cannabinoids Found In Cannabis Flower

The cannabis plant holds an incredible variety of compounds, and the different types of cannabinoids are some of its most fascinating features. These natural compounds interact with the body in unique ways, shaping the effects you feel. Some are well-renowned, like THC and CBD, while others—CBG, CBC, or THCv—are still gaining attention.

Did you know scientists have identified over 100 cannabinoids so far, and there could be many more waiting to be found? Each one has its own personality, flavor, and potential benefits. You might be interested in calming options or in those with more euphoric effects. Keep reading to find out more!

What Are Cannabinoids and How Do They Work?

Cannabinoids are compounds that interact with your body’s endocannabinoid system (ECS). This system helps regulate functions like mood, appetite, pain, and rest. Cannabinoids connect with CB1 and CB2 receptors found in your brain and throughout your body. When you consume cannabis or hemp products, these compounds influence how you feel, creating effects that range from euphoric to calming depending on the cannabinoid type.

Plant-Based vs. Endogenous Cannabinoids

Plant-based cannabinoids, also called phytocannabinoids, come directly from cannabis and hemp plants. Popular examples include THC, CBD, and CBG. Endogenous cannabinoids, or endocannabinoids, are made naturally in your body, such as anandamide and 2-AG. Both types work with the ECS to maintain internal balance, but only plant-based cannabinoids come from external sources like flower, concentrates, or edibles you can consume.

What Are the Different Types of Cannabinoids?

The cannabis plant produces many cannabinoid compounds, each with unique effects on the human body. Some are widely known, while others are only found in trace quantities but still influence how cannabinoids interact with your body’s endocannabinoid system.

Major vs. Minor Cannabinoids

Major cannabinoids include the primary psychoactive compound tetrahydrocannabinol (THC) and the non-psychoactive cannabidiol (CBD). These dominate most cannabis products and are found naturally in higher concentrations.

Minor cannabinoids, such as cannabigerol (CBG), cannabinol (CBN), and cannabichromene (CBC), appear in cannabis in trace quantities. Each produces unique effects, with certain cannabinoids among them showing promising therapeutic potential. Both major and minor cannabinoids work through cannabinoid receptors in the central nervous system to influence how your body responds.

Acidic Cannabinoids (THCa, CBDa, etc.)

Acidic cannabinoids are the raw forms of well-known compounds found in the cannabis sativa plant before heat or age changes them. Examples include tetrahydrocannabinolic acid (THCa) and cannabidiolic acid (CBDa). THCa does not cause psychoactive effects until heated, converting into THC. CBDa converts into CBD through the same process.

These cannabis-derived compounds are found naturally in the hemp plant and cannabis strains. Acidic cannabinoids produce different forms of therapeutic effects and are a focus of experimental therapeutics and integrative health research.

How Many Cannabinoids Are There in Cannabis?

Scientists have identified more than 100 cannabinoid compounds in the cannabis sativa plant, with many found naturally in only trace quantities. Research supported by the leading scientific institutes and other scientific service portals continues to reveal other cannabinoids, synthetic compounds, and their potential therapeutic effects in cannabis products.

Identified Compounds So Far

The cannabis plant produces a wide range of natural cannabinoids, including tetrahydrocannabinol (THC), cannabidiol (CBD), cannabinol (CBN), and many lesser-known cannabinoids like CBG and CBC. Each interacts differently with CB2 receptors and the brain, influencing effects of cannabinoids such as psychoactive effects, discomfort relief, or non-psychoactive therapeutic potential. These chemical compounds are closely related but vary in potency, presence in cannabis strains, and how the body responds.

Potential for Discovery and Research Expansion

The list of cannabinoids isn’t final. Cannabis-derived compounds continue to be studied by the National Institute, the European Journal, and other integrative health resources. Experimental therapeutics suggest certain cannabinoids might offer new therapeutic effects or alleviate pain without the negative effects linked to drug abuse. As cannabis use becomes more accepted under federal law, researchers expect to identify different forms of cannabinoids, synthetic cannabinoids, and compounds with unique benefits.

THC and Its Variants

THC, or tetrahydrocannabinol, is the primary psychoactive compound in the cannabis plant. These variants differ in potency, effects, and presence in cannabis strains or hemp plant products.

• Delta-9 THC (Tetrahydrocannabinol). The primary psychoactive compound in cannabis that interacts with cannabinoid receptors in the brain and central nervous system. It produces psychoactive effects such as changes in motor coordination, mood, and perception. Found naturally in higher doses in marijuana and in smaller amounts in hemp.
• Delta-8 THC. Closely related to Delta-9 but with milder psychoactive effects. Delta-8 THC is said to be 1/2 to 2/3 the strength of Delta-9 THC. It interacts with cannabinoid receptors differently from regular THC, offering a smoother experience for some consumers. Found naturally in trace quantities in the cannabis sativa plant and often converted from hemp-derived cannabidiol (CBD).
• Delta-10 THC. A lesser-known cannabinoid found in small amounts in the cannabis sativa plant. Delta-10 is reported to be about 70% as potent as Delta-8. It's often created from synthetic compounds and sold legally in certain areas. Known for a more uplifting effect and subtle euphoria while still engaging the body’s endocannabinoid system.
• THCa (Tetrahydrocannabinolic Acid). A non-psychoactive cannabinoid found naturally in raw cannabis and hemp. Heating converts it into THC at a return rate of 87.7%, producing psychoactive effects. Consuming it raw avoids intoxication while retaining potential therapeutic effects studied in complementary and integrative health research.
• THCp (Tetrahydrocannabiphorol). A cannabinoid discovered in 2019 that’s structurally similar to Delta-9 THC but has a longer alkyl side chain, allowing it to bind more strongly to CB1 receptors. Studies suggest THCp may be up to 33 times more potent than Delta-9 THC. Found naturally in trace amounts in cannabis, it’s often derived from hemp cannabinoids through advanced extraction and conversion methods. Its effects may include stronger euphoria, more pronounced mood changes, and intensified body sensations compared to Delta-9 THC.

CBD and CBDa

CBD, or cannabidiol, is one of the most recognized natural cannabinoids in the cannabis sativa plant. CBDa, its acidic precursor, changes into CBD when exposed to heat. Both are non-psychoactive and interact with the body’s endocannabinoid system in unique ways.

• CBD (Cannabidiol). A non-psychoactive cannabinoid found naturally in hemp plant varieties and certain cannabis strains. CBD interacts with cannabinoid receptors without causing the psychoactive effects of THC. Many cannabis products use CBD for its potential therapeutic effects and role in the entourage effect alongside other cannabinoids.
• CBDa (Cannabidiolic Acid). The raw, unheated form of CBD is found naturally in freshly harvested cannabis and hemp. It does not produce psychoactive effects and is being studied in complementary and integrative health research for its potential therapeutic benefits. Heating CBDa through smoking, vaping, or cooking converts it into CBD, making it one of the key cannabis-derived compounds in modern cannabis use.

Lesser-Known Cannabinoids Worth Knowing

Beyond THC and CBD, the cannabis plant produces other cannabinoids in smaller amounts. These lesser-known cannabinoids can still influence how cannabinoids interact with the body’s endocannabinoid system and may contribute to the entourage effect.

• CBN (Cannabinol). Found naturally as THC ages and oxidizes. CBN is mildly psychoactive but far less potent than THC. Some cannabis products, like our sleep gummies, include CBN for its potential role in promoting relaxation and aiding functional wellness.
• CBG (Cannabigerol). Often called the “mother cannabinoid” because it’s a precursor to THC, CBD, and other cannabinoids. Found in trace quantities in most cannabis strains, CBG interacts with both CB1 and CB2 receptors and may offer unique therapeutic potential.
• CBC (Cannabichromene). A non-psychoactive cannabinoid that appears in certain cannabis sativa plant varieties. CBC is being studied in complementary and integrative health research for possible roles in supporting mood, pain relief, and other therapeutic effects when combined with THC and CBD.

Rare and Emerging Cannabinoids

Some cannabinoids appear in trace quantities or have only recently been identified in the cannabis sativa plant. These rare cannabinoids are gaining attention for their unique properties and potential roles in cannabis products.

• THCv (Tetrahydrocannabivarin). A cannabinoid compound closely related to Delta-9 THC but with different psychoactive effects. Found naturally in certain cannabis strains, THCv interacts with cannabinoid receptors in ways that may offer distinct functional effects compared to THC and CBD.
• CBDv (Cannabidivarin). A non-psychoactive cannabinoid found naturally in the hemp plant and select cannabis varieties. CBDv is structurally similar to cannabidiol (CBD) and is being examined in experimental therapeutics for its potential role in integrative health applications.
• CBL, CBT, and Others. These lesser-known cannabinoids appear in very small amounts and are often detected during advanced cannabis research. The effects of these cannabinoids on the human body are not fully understood, but they may contribute to the entourage effect and offer new therapeutic potential when combined with other cannabinoids in cannabis-derived compounds.

Non-Euphoric Cannabinoids vs. Euphoric Ones

Cannabinoids produce different forms of effects depending on how they interact with cannabinoid receptors in the brain and central nervous system. Some are non-psychoactive, offering therapeutic potential without intoxication, while others create psychoactive effects that can alter mood, perception, and motor coordination while still providing therapeutic benefits.

Which Cannabinoids Make You Feel “Elevated”?

Cannabinoids like Delta-9 tetrahydrocannabinol (THC), Delta-8 THC, and THCv are primary psychoactive compounds in the cannabis sativa plant. These cannabinoids interact with CB1 receptors in the brain, producing euphoric effects and influencing mood. Higher doses may intensify the effects of THC, while certain cannabinoids vary in potency based on cannabis strains and how the body responds.

Which Offer Clear-headed or Functional Effects?

Non-psychoactive cannabinoids such as cannabidiol (CBD), cannabigerol (CBG), and cannabichromene (CBC) do not produce intoxication. These natural cannabinoids interact mainly with CB2 receptors, supporting complementary and integrative health research into potential therapeutic effects. Unlike THC, they may help promote clarity and focus in cannabis use while contributing to the entourage effect alongside other cannabinoids.

Synergy Between Cannabinoids: The Entourage Effect

The entourage effect describes how cannabinoids interact with each other and with terpenes in the cannabis plant. When combined, certain cannabinoids produce more noticeable or balanced effects compared to isolated compounds, influencing both psychoactive effects and therapeutic potential.

Why Full-Spectrum Products May Work Differently

Full-spectrum cannabis products contain a variety of cannabinoid compounds, including THC and CBD, along with other cannabinoids and terpenes. This mix may enhance the effects of cannabinoids on the human body’s endocannabinoid system, offering different forms of therapeutic potential not always found in single-compound cannabis products.

How Cannabinoids + Terpenes Interact

Terpenes are aromatic compounds found in cannabis that give each strain its distinct scent and flavor profile, like citrusy, piney, or earthy notes. Beyond aroma, they may also influence the plant’s effects by interacting with cannabinoids such as THC and CBD in what’s known as the entourage effect.

Cannabinoids and terpenes work together by binding to cannabinoid receptors in the central nervous system and brain. This interaction can influence mood, perception, and physical responses. Cannabis-derived compounds with terpene diversity are often preferred by consumers seeking a broader range of effects, from discomfort relief to appetite support, while minimizing potential negative effects.

What Are the Benefits of Different Cannabinoids?

Different types of cannabinoids produce unique effects depending on how they interact with cannabinoid receptors in the human body. Some target the brain and central nervous system, while others act on CB2 receptors throughout the body. The combination of cannabinoids in cannabis products can influence both psychoactive effects and potential therapeutic benefits.

Functional Support (Mood, Sleep, Calm, Clarity)

Certain cannabinoids like cannabidiol (CBD), cannabinol (CBN), and cannabigerol (CBG) are non-psychoactive and found naturally in the hemp plant. These cannabinoid compounds are being explored in complementary and integrative health research for their potential to promote rest, relaxation, and focus. Unlike THC, these cannabinoids interact differently with the body’s endocannabinoid system, potentially supporting mood and clarity without intoxication. THC is also known for promoting quality sleep and positive mood while producing an enjoyable buzz.

Plant-Based Wellness Potential

Cannabis-derived compounds, including THC and CBD, may offer therapeutic potential when consumed responsibly. The entourage effect shows how other cannabinoids and terpenes can work together to enhance benefits. Research from groups like the National Cancer Institute and the European Journal continues to examine how cannabis sativa plant varieties and certain cannabinoids could help soothe physical discomfort, promote well-being, and offer different forms of functional support.

Can You Consume Multiple Cannabinoids Together?

You can consume multiple types of cannabinoids to create layered effects. When cannabinoids interact, they may enhance therapeutic potential through the entourage effect. Choosing cannabis products with THC and CBD, along with other cannabinoids, lets the body respond in different forms. Always check product labels and COAs to confirm cannabinoid compounds and compliance with federal law.

Cannabinoids in Cheef Botanicals Products

Cheef Botanicals offers cannabis-derived compounds in multiple forms, each with unique ways to consume and enjoy them. All products are lab-tested with COAs to ensure purity, potency, and compliance with federal law.

THCa Products

THCa provides non-psychoactive effects when consumed raw, such as in salads or smoothies, but heating it through smoking, vaping, or baking converts it into THC for psychoactive effects.

• THCa Flower. Strains like Gelato and Pineapple can be smoked, vaped, or used in edibles. Some are also available as ready-to-use pre-rolls for convenience.
• THCa Concentrates. Diamonds (Spritzer strain) and Live Rosin (Lemon Cherry Gelato) are ideal for dabbing, offering higher potency for experienced consumers.
• THCa Gummies (Watermelon OG). Nano-infused for faster onset when eaten, combining fruity flavor with precise dosing. Also includes Delta 9-THC to provide a blissful buzz.

CBD and CBN Options

CBD and CBN are non-psychoactive cannabinoids that can be consumed in smokable, edible, or vapor form. They are often chosen for their versatility and role in the entourage effect.

• CBD Flower. Northern Lights delivers a smooth, earthy smoke or vape. Also available in pre-roll form.
• CBD + CBN Gummies for Sleep. Combines hemp-derived CBD and CBN with melatonin for nighttime use.

THCp and Other Multi-Cannabinoid Edibles

THCp is more potent than many cannabinoids and is often blended with others for balanced effects.

• THCp + Delta-9 THC + HHC Gummies. Chewable edibles that combine three cannabinoids for layered results.
• THCp Flower. Hemp flower infused with THCp distillate, best enjoyed by smoking or vaping.

Are Cannabinoids Legal?

Cannabinoid legality depends on their source and THC content. Hemp-derived cannabinoids with 0.3% Delta-9 THC or less are federally legal under the 2018 Farm Bill, while marijuana-derived cannabinoids remain restricted under federal law. State laws vary, so always check local regulations before purchasing cannabis products.

Hemp-Derived vs. Marijuana-Derived Cannabinoids

Hemp plant cannabinoids, including CBD and certain THC variants, are legal when sold with verified COAs showing THC compliance. Marijuana-derived compounds, even with therapeutic potential, are federally illegal but may be allowed under state cannabis use laws.

Federal and State Law Considerations

Federal law allows hemp-based cannabinoids to be sold legally with compliant THC levels, while states regulate cannabis use differently. Some restrict synthetic cannabinoids or certain cannabinoids like Delta-8 THC. Always review product sourcing, lab results, and local legislation before purchasing or consuming cannabis-derived compounds.

Choosing the Right Type of Cannabinoid for You

Choosing the right cannabinoid depends on your goals, preferred effects, and how your body responds. Always check COAs and ensure compliance with federal law.

• Consider Your Intent. Delta-9 THC offers psychoactive effects, while CBD, CBG, and CBC are non-psychoactive. CBN is often chosen for relaxation.
• Read Labels and COAs. Verify cannabinoid content, THC percentage, and whether it contains natural cannabinoids, synthetic cannabinoids, or blends.
• Match to Products. Full-spectrum cannabis products combine multiple cannabinoids for the entourage effect, while isolates offer a single compound.
• Know Local Laws. Even hemp-derived cannabinoids sold legally under federal law may face state restrictions.

Final Thoughts – Types of Cannabinoids in Cannabis

The many types of cannabinoids in the cannabis plant offer different effects and uses. Delta-9 THC is the primary psychoactive compound, while CBD and CBN are non-psychoactive and found naturally in hemp. These cannabinoids interact with the body’s endocannabinoid system in unique ways. Full-spectrum cannabis products may combine several cannabinoids for the entourage effect, while isolates provide a single compound.

Cheef Botanicals offers hemp plant–based options like THCa flower and CBD gummies, all lab-tested for quality and federal law compliance. Choosing the right cannabis-derived compounds means knowing your goals, preferred effects, and local laws. Always buy from trusted sources for safe cannabis products.